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From Daniel Island? You'd still have to jump onto 526 and cross over 26 until it dumped onto 17 (which would then be mixing with everyone else coming from Summerville/North Charleston).
You might be able to bypass a few things by turning off onto Rivers and following that south a bit until you had better access to 26 (or sticking with it all the way into downtown). 526/26 is probably still your best bet, and it's a very quick drive if traffic's light.
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