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Old 03-10-2013, 03:16 PM
 
200 posts, read 274,003 times
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Global variation in copy number in the human genome

12 % of the DNA Differs Amongst Human Races and Populations - Softpedia

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The Human Genome Project found all humans to have a 99.9 % similar genetic content and identity, but this is challenged by a new more detailed research suggesting a higher genetic diversity, with further medical and evolutionary implications.

Previous studies focused on analyzing polymorphism (variation) in DNA nucleotidic bases. But the new approach tackled deletions or duplications of code among relatively long sequences of individual DNA and then compared the so-called copy number variations (CNVs) across individuals from different human breeds. This method uncovered a complex, higher-order variation in the code and better explains why some populations or races are vulnerable to certain diseases and respond well to specific drugs, while counterparts swiftly fall sick or never respond to treatment.

Two technical breakthroughs, a faster, accurate sequencing of DNA and a powerful software programme to spot the CNVs allowed the new approach. 1,447 CNVs were located in roughly 2,900 genes, which means around 12 % of the human DNA. "Each one of us has a unique pattern of gains and losses of complete sections of DNA," said Matthew Hurles from Britain's Wellcome Trust Sanger Institute. "One of the real surprises of these results was just how much of our DNA varies in copy number. We estimate this to be at least 12 % of the genome."
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Old 03-10-2013, 10:16 PM
 
23,597 posts, read 70,412,676 times
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Fine by me. What is your point?
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Old 03-11-2013, 04:45 AM
 
15,912 posts, read 20,198,598 times
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Isn't it amazing the more technically advanced we get the more we find out the less we know?
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