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Old 04-27-2024, 04:34 PM
 
17,633 posts, read 13,420,761 times
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https://www.sciencealert.com/cannabi...-study-reveals
Quote:
Using cannabis may cause changes in the human body's epigenome, a study of over 1,000 adults suggests. The epigenome functions like a set of switches, activating or deactivating genes to change how our bodies function.



"We observed associations between cumulative marijuana use and multiple epigenetic markers across time," Lifang Hou, a preventative medical doctor and epidemiologist from Northwestern University Feinberg School of Medicine explained in July 2023.




Cannabis is a commonly used substance in the United States, with 49 percent of people trying it at least once, Hou and a team of US researchers report in their published paper. Some US states and other countries have made it legal, but we still don't fully understand its effects on our health.
It may be legal in many states and even when still illegal, still highly used by many many people, we still do not know all health dangers.


As always, be careful out there!
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Old 04-28-2024, 05:12 AM
 
Location: The Driftless Area, WI
7,303 posts, read 5,185,498 times
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Epigenetics is a relatively new area of study. We're really just in the information gathering stage, and we don't know what the info means.....DNA is subject to chemical changes (often by adding a methyl group to the sugar backbone of the DNA) which may serve to activate or de-activate that gene..,Apparently this paper found that dope users have more of those changes than non-users....(? which is cause, which is effect?)

A big review of cannabis use was published in NEJM 10 or 15 y/a. They found little evidence that casual use caused any problems at all....While there may be no physical harm, I personally wonder about the mental health of those who feel compelled to use the stuff. It's such a pity that some people have to resort to use of chemicals to induce a feeling of happiness.
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Old 04-28-2024, 06:23 AM
 
9,936 posts, read 4,693,984 times
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Not surprising since it's used for pain in some cases ie nervous system.. Since they say it can remain in system for 30 days without the high the questions is what are those remaining chemicals doing if not making a person high.
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Old 04-29-2024, 09:36 AM
 
Location: Juneau, AK + Puna, HI
10,588 posts, read 7,812,749 times
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Yes, this is not surprising. Alcohol and tobacco have also been linked to undesirable epigenetic changes.
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Old 04-29-2024, 05:55 PM
 
Location: New Zealand
405 posts, read 108,769 times
Reputation: 211
Quote:
Originally Posted by guidoLaMoto View Post
Epigenetics is a relatively new area of study. We're really just in the information gathering stage, and we don't know what the info means.....DNA is subject to chemical changes (often by adding a methyl group to the sugar backbone of the DNA) which may serve to activate or de-activate that gene..,Apparently this paper found that dope users have more of those changes than non-users....(? which is cause, which is effect?)

A big review of cannabis use was published in NEJM 10 or 15 y/a. They found little evidence that casual use caused any problems at all....While there may be no physical harm, I personally wonder about the mental health of those who feel compelled to use the stuff. It's such a pity that some people have to resort to use of chemicals to induce a feeling of happiness.
I see it as being used more to induce a feeling of being stoned, not happy - more typically an introspective feeling imo

Last edited by sandshark; 04-29-2024 at 06:11 PM..
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Old 05-06-2024, 03:14 PM
 
50,980 posts, read 36,672,261 times
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Quote:
Originally Posted by guidoLaMoto View Post
Epigenetics is a relatively new area of study. We're really just in the information gathering stage, and we don't know what the info means.....DNA is subject to chemical changes (often by adding a methyl group to the sugar backbone of the DNA) which may serve to activate or de-activate that gene..,Apparently this paper found that dope users have more of those changes than non-users....(? which is cause, which is effect?)

A big review of cannabis use was published in NEJM 10 or 15 y/a. They found little evidence that casual use caused any problems at all....While there may be no physical harm, I personally wonder about the mental health of those who feel compelled to use the stuff. It's such a pity that some people have to resort to use of chemicals to induce a feeling of happiness.

I don't think using it casually is any different than drinking casually. What makes you think they :have to resort" to cannabis, while wine drinkers are simply choosing a drug that makes them feel relaxed?
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Old 05-06-2024, 03:16 PM
 
50,980 posts, read 36,672,261 times
Reputation: 76756
Quote:
Originally Posted by anononcty View Post
Not surprising since it's used for pain in some cases ie nervous system.. Since they say it can remain in system for 30 days without the high the questions is what are those remaining chemicals doing if not making a person high.

Nothing. It is stored in fat, so it stays until the fat i burned off, but it doesn't have any effects on the body then. Just like fat soluble vitamins get stored in fat, like A, D, E, while others like B vitamins are water soluble.
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Old Yesterday, 04:48 AM
 
Location: U.S.A.
19,748 posts, read 20,304,760 times
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Quote:
Originally Posted by ocnjgirl View Post
I don't think using it casually is any different than drinking casually. What makes you think they :have to resort" to cannabis, while wine drinkers are simply choosing a drug that makes them feel relaxed?
True. Plus, alcohol makes people fat.
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Old Yesterday, 06:58 AM
 
50,980 posts, read 36,672,261 times
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Quote:
Originally Posted by D217 View Post
True. Plus, alcohol makes people fat.

Well, pot does that too, with the munchies. When I was young and in 7-11 microwaving cheeseburgers at 3am, that was booze. At home eating a chicken pot pie followed by a sleeve of Oreos was pot, lol.
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Old Yesterday, 09:36 PM
 
1,038 posts, read 563,265 times
Reputation: 2746
Key word warning here...."may". So this is a meaningless study to me. Also, ONE study is worthless, you have to have multiple studies done by reputable medical facilities and doctors, and you have to know who is paying for the studies.

When one of the founders of this alleged publication above is listed as "a failed neuroscientist"!!! Hmmm, I am a wee bit cautious about it, LOL!

Where do you folks find these things? Please, go to Scientific American (which is not great, but gooder than the publication above) or other reputable publications.
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