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Old 01-21-2024, 05:23 PM
 
15,592 posts, read 15,662,820 times
Reputation: 21998

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I've run into something like this - though luckily not so serious.



The FDA warned an asthma drug could induce despair. Many were never told.
Children face the greatest risks of the drug’s ill effects, and while usage by minors did decline, it was still taken by 1.6 million of them — including Nicole Sims’ son. Sims had no idea why, at 6, her son started having nightmares and hallucinations of a woman in the window.
https://www.sltrib.com/news/nation-w...ma-drug-could/
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Old 01-22-2024, 04:58 AM
 
Location: The Driftless Area, WI
7,249 posts, read 5,123,089 times
Reputation: 17742
???? Another bit of stupidity from The Feds to benefit the trial lawyers?

The studies showed no significant differences in rates of depression, self-harm or suicide among the med users vs general population https://www.fda.gov/drugs/drug-safet...d-allergy-drug scroll down to "data" if you're in a hurry.....The self-admitted "weakness" in the data is that it included only reported problems, and was not a double-blind, case/control prospective study.
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Old 01-22-2024, 07:19 AM
 
Location: SW Florida
14,938 posts, read 12,136,035 times
Reputation: 24806
Well, I don't know about despair, but Singulair, or its generic counterpart monteleukast has been my daughter's go to medication in controlling her asthma, and it would seem other inflammatory processes since she was a child. It's still very effective for her in this regard.

I recall paying $100 a month for the Singulair prescription before the generic became available- that was with the insurance-, but we found the cost worth it due to how well her asthma was controlled with the drug. She found the generic form was just as effective, thank goodness as the cost of her prescriptions for the monteleukast were a fraction of the brand name and she could get a 90 day supply. She's gone through a period of time within the last couple years where she went without the monteleukast- thanks to a pharmacy screwup ( they claimed they had filled a 3month supply of the med but had not, and said they would not fill it again for 3 months, and she ran out) She should have appealed to her insurance company but didn't, so she was partially responsible. She was reminded again, how effective the monteleukast was at controlling her asthma as she had a number of exacerbations of both asthma, and allergic reactions to who knows what resulting in skin rashes in the period of time she went without the drug. These disappeared when she was able to get the drug once more.

So I hope the FDA doesn't decide to take the Singulair off the market, or limits its availability in a knee jerk reaction to this "finding" reported by whoever it is and for whatever motive they may have in doing so.
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Old 01-22-2024, 09:59 AM
 
Location: The Driftless Area, WI
7,249 posts, read 5,123,089 times
Reputation: 17742
Yea, don't argue with success.

Side effects occur in X% of users-- but that's the experience over the total population of users. For any individual user, it's either 100% or 0%--- one guy can't get X% of a side effect.

I couldn't access the article in the OP, but for the one I cited, they found 45 suicides among 450,000 teenage users- that's 1 in 10,000...Given that the suicide rate for teens in the general population is 1.2 in 10,000 (and rising), we could make a case that this stuff is a good treatment for suicide.
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