Phoenix Sky Harbor Airport is located approximately 12 miles to the west of Mesa and is served by 21 airlines that connect the East Valley area to 109 cities in the United States and around the world. Sky Harbor is a major hub for Southwest and America West airlines but also has services through airlines such as United, Delta Frontier, and Sun Country. Non-stop international flights are available via Aeromexico, Air Jamaica, British Airways, Lufthansa, Air Canada, and America West Airlines. The local airfields, Williams Gateway and Falcon Field, offer charter flights in the southwest.
Several freeways, U.S. highways and state highways pass through or near Mesa, including U.S. 60 (known as Superstition Freeway) and state highways 87 and 89. The Santan Freeway 202 creates a bypass around the more congested downtown area, and Interstates 10 and 17 are quickly accessible from the city. Greyhound Bus service maintains a branch in Mesa, with daily departures and arrivals.
Mesa is laid out on a straightforward north-south, east-west grid pattern as regards its major streets. Center Street and Main Street are perpendicular to each other and, as suits their names, intersect in the city center in a manner that provides a handy reference point and makes city navigation relatively easy.
Bus service within Mesa is provided by Valley Metro, which runs buses 6 days a week for about 16 hours per day. There are 9 local routes and 4 express routes to Phoenix. Mesa operates a Dial-A-Ride program for people with mobility or vehicle operation issues, plus the city offers RideChoice options to elderly and disabled patrons who either use the bus, cabs or are driven to their destinations by friends or family members.
Mesa has styled itself as a bicycle-friendly city, with 70 miles of bicycle routes and 40 miles of bicycle lanes. The city plans for more bicycle route and lane construction in the future, along with facilities at bike destinations.